Selpercatinib
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Selpercatinib is a medicine used to treat certain types of cancer. It's a targeted therapy, which means it targets specific molecules in cancer cells to stop them from growing and spreading.
This medicine is mainly used for people with a type of cancer called non-small cell lung cancer (NSCLC). Specifically, it's for those who have a specific change, or mutation, in their genes called RET fusion or RET mutations. These mutations can make cancer cells grow faster and spread to other parts of the body.
Selpercatinib works by blocking the activity of a protein called RET. When RET is mutated, it sends signals to cancer cells to grow and divide uncontrollably. By blocking RET, selpercatinib helps stop the cancer cells from growing and spreading.
Doctors usually prescribe selpercatinib when other treatments haven't worked or if the cancer has spread to other parts of the body. It comes in the form of capsules that you take by mouth, usually once or twice a day, depending on your doctor's instructions.
Before starting selpercatinib, our doctor will likely do tests to make sure it's the right treatment for you. They might check if you have the specific mutations that selpercatinib targets. They'll also monitor you closely while you're taking the medicine to see how your body responds and if you experience any side effects.
Like all medicines, selpercatinib can cause side effects. Common side effects include tiredness, constipation, muscle or joint pain, high blood pressure, and changes in liver function tests. Some people may also experience more serious side effects, such as problems with their heart rhythm or bleeding in the stomach or intestines. It's important to tell our doctor if you experience any side effects while taking selpercatinib.
In some cases, your doctor may need to adjust your dose or temporarily stop treatment if you experience side effects. It's essential to follow our doctor's instructions closely and to communicate with them about any concerns or changes in your health.
Overall, selpercatinib is an important treatment option for people with certain types of cancer, particularly those with NSCLC and specific genetic mutations. It offers hope for patients who may not have responded well to other treatments and can help improve quality of life by slowing down the progression of the disease. However, like all cancer treatments, it's essential to weigh the benefits against the potential risks and to work closely with your healthcare team to determine the best treatment plan for you.
Have any queries, book a consultation with our Oncology Clinical Specialist
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How does this medicine work
Selpercatinib is like a superhero medicine for certain types of cancer, especially one called non-small cell lung cancer (NSCLC). It's designed to fight against specific changes, or mutations, that happen in the genes of cancer cells. These mutations can make the cancer cells grow and spread out of control.
The way selpercatinib works is by targeting a protein called RET. Think of RET as the boss of the cancer cells. When RET gets messed up due to those mutations, it tells the cancer cells to keep multiplying and spreading, causing trouble in the body.
But here comes selpercatinib to the rescue! It's like a shield that blocks RET from sending those bad signals to the cancer cells. So, when the cancer cells don't get those signals, they can't grow and spread like they used to. This helps slow down the cancer and gives the body a chance to fight back.
Selpercatinib usually comes in the form of little capsules that you take by mouth, kind of like swallowing a small pill. You might need to take it once or twice a day, depending on what your doctor thinks is best for you.
Of course, like any superhero, selpercatinib can have side effects. Some people might feel tired, or they could have tummy troubles like constipation. It might also affect things like blood pressure or how well your liver works. But don't worry—your doctor will keep an eye on you and help you manage any side effects that pop up.
Overall, selpercatinib is a pretty cool medicine that gives hope to people battling certain types of cancer. It's not a cure, but it can be a powerful weapon in the fight against cancer, helping to keep it under control and improve quality of life.
Have any queries, book a consultation with our Oncology Clinical Specialist
What is useful for?
Selpercatinib is a helpful medicine for a specific type of cancer called non-small cell lung cancer (NSCLC). It's especially useful for people who have certain changes, or mutations, in their genes known as RET fusion or RET mutations. These mutations can make cancer cells grow and spread quickly.
So, if someone has NSCLC with these mutations, selpercatinib can be a good treatment option. It works by blocking a protein called RET, which is like the boss of the cancer cells, telling them to grow and spread. By blocking RET, selpercatinib helps slow down the cancer's growth and stops it from spreading to other parts of the body.
In simpler terms, selpercatinib is like a superhero medicine that fights against certain types of lung cancer, giving hope to people who need it most.
Visit our Research Division Doctors in Online Consults for more details.
What if you miss the dose?
If you forget to take your selpercatinib dose, don't worry too much. Just take it as soon as you remember, unless it's almost time for your next dose. If that's the case, just skip the missed dose and take your next one as usual.
It's important not to take extra doses to make up for the one you missed. Taking too much selpercatinib at once could increase your chances of having side effects.
If you're ever unsure about what to do, it's best to check with your doctor or pharmacist. They can give you advice on how to handle missed doses and help you stay on track with your treatment.
Please book a consultation with our Oncology Clinical Specialist to know more about what happens if you miss the dose.
Will there be Side Effects
There can be side effects when using selpercatinib, just like with many other medicines. Some people might feel tired or have stomach problems like constipation. It can also affect things like blood pressure and liver function.
But don't worry too much! Not everyone will experience side effects, and they might not be too serious for those who do. Plus, our doctor will keep an eye on you and help you manage any side effects that come up.
It's essential to talk to your doctor about any concerns you have about side effects. They can give you advice on how to deal with them and make sure you're getting the most benefit from your treatment.
Have any queries, book a consultation with our Oncology Clinical Specialist
Tell us if you are taking other medicines like:-
If you're taking other medicines along with selpercatinib, it's important to let our doctor know. Mixing medicines can sometimes cause problems, so our doctor needs to make sure they're safe to take together.
Our doctor might need to adjust your doses or keep an eye on you for any side effects. So, it's best to be honest and tell them about any other medicines you're taking, including over-the-counter drugs and supplements.
By working together with our doctor, you can make sure you're getting the right treatment and staying safe while taking selpercatinib.
Have any queries, book a consultation with our Oncology Clinical Specialist
Safety Advice : Pregnancy, Liver or Kidney Damaged
Here's some advice about the safety of using selpercatinib:
1. **Pregnancy:** If you're pregnant or planning to get pregnant, it's important to tell our doctor. Selpercatinib might not be safe for the baby, so your doctor can help you decide on the best course of action.
2. **Liver Damage:** If you have any liver problems or diseases, it's essential to let our doctor know. Selpercatinib can affect how well your liver works, so they'll need to monitor you closely and adjust your treatment if necessary.
3. **Kidney Damage:** Similarly, if you have kidney issues, it's crucial to tell our doctor. They can determine if selpercatinib is safe for you to take and keep an eye on your kidney function during treatment.
By being open with our doctor about your health history and any concerns you have, you can work together to ensure that selpercatinib is the right treatment for you and that you stay safe while taking it.
Have any queries, book a consultation with our Oncology Clinical Specialist
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